个人简介：

谭碧娥，二级教授。主要从事猪肠道发育和营养调控研究。先后主持国家自然科学基金项目5项、国家重点研发计划课题、国家科技支撑计划专题、973项目子课题等。近年来以第一/通讯作者发表SCI收录论文80多篇， SCI论文合计引用1000多次，单篇最高被引400多次；参编著作4部，申请发明专利9项，获国家自然科学奖二等奖（排名第2）、中华农业科技奖一等奖（排名第5）和创新团队奖（排名第5）、湖南省自然科学一等奖（排名第2）和二等奖（排名第3）以及中科院青年创新促进会优秀会员、中国农学会青年科技奖、中科院广州分院优秀青年科学家奖、中国科学院经理优秀奖。获“庆祝中华人民共和国成立70周年纪念章”、九三学社庆祝新中国成立七十周年优秀社员、湖南省三八红旗手、英国威廉希尔公司2020年“年度人物”荣誉称号。现为现代农业产业技术体系饲料营养价值评价与资源利用岗位科学家、畜禽产品品质调控湖南省重点实验室主任、中国畜牧兽医学会动物营养学分会理事。入选国家级青年人才、领军人才。

教育及科研经历：

2001.07    动物医学       农学学士    英国威廉希尔公司

2010.07     动物生态营养    理学博士    中国科学院亚热带农业生态所

研究经历：

2008年02月-2009年01月  访问学者  美国德州农工大学

2016年12月-2017年12月  访问学者  美国加州大学戴维斯分校

2010年8月-2019年12月 助理研究员/副研究员/研究员 中国科学院亚热带农业生态所

2019年12月至今             神农学者特聘教授 英国威廉希尔公司

主要研究方向：

1. 猪营养生理调控

2. 饲料资源开发与利用

联系方式：

Email：bietan@hunau.edu.cn，bietan0412@hotmail.com

地址：英国威廉希尔公司第二教学楼502

科研奖励：

(1)  2021年，中国科学院生猪生态养殖营养调控创新团队，2020-2021年度神农中华农业科技奖，排名第5

(2) 2019年，“壳寡（聚）糖对动物营养生理的调控作用及机理研究”，湖南省自然科学二等奖，排名第3

(3)  2016年，“猪日粮功能性氨基酸代谢与生理功能调控机制研究”，国家自然科学奖二等奖（排名第2）2016-Z-105-2-03-R02

(4)  2014-2015 年，“猪氨基酸营养功能的研究与技术集成推广”，中华农业科技奖一等奖，排名第5

(5)  2013年，“猪氨基酸营养功能的基础研究”，湖南省自然科学一等奖，排名第2

(6) 2020年，中国农学会青年科技奖

(7) 2017年，中科院广州分院优秀青年科学家奖

在研项目：

(1) 2019.12-2024.12   英国威廉希尔公司人才引进科研启动费，500万元

(2) 2021.01-2024.12   国家自然科学基金区域创新发展联合基金重点支持项目” 基于肠道微生物研究宁乡猪母体对粗饲料的利用及其影响子代肠道发育的机制”（U20A2054），257万元

(3) 2021.01-2024.12    国家自然科学基金面上项目“仔猪肠道MyD88通过自噬调节氧化应激反应的机制及营养调控”（32072745），58万元

(4) 2021.12-2024.11国家重点研发计划课题“非粮蛋白饲料提质增效关键技术及产品创制”（2021YFD1301004），1325万元

(5) 2021.12-2026.11 国家重点研究计划子课题“母猪动态营养需要与营养精准供给技术”（2021YFD1300401），66万元

(6) 2021.01-2025.12现代农业产业技术体系岗位科学家 （CARS-35），275万元

代表性论文（近3年）：

(1) Feng L, Luo Z, Wang J, Wu K, Wang W, Li J, Ma X*, Tan B*. Fermentation characteristics of different sources of dietary fiber in vitro and impacts on growth performance, nutrient digestibility and blood para-meters of piglets. Journal of Functional Foods, 2023, 108: 105761.

(2) Hussain T, Kandeel M, Metwally E, Murtaza G, Kalhoro DH, Yin Y, Tan B^*, Chughtai MI, Yaseen A, Afzal A, Kalhoro MS. Unraveling the harmful effect of oxidative stress on male fertility: A mechanistic insight. Frontiers in Endocrinology, 2023,14:1070692.

(3) Wang J, Li Y, Cao C, Yang R, He M, Yan J, Huang P, Tan B^*, Fan Z^*. The periparturient gut microbiota’s modifications in Shaziling sows concerning bile acids. Metabolites 2023, 13, 68.

(4) Li M, Huang Y, Jin H, Yuan D, Huang K, Wang J, Tan B^*, Yin Y. Vitamin A ameliorated irinotecan-induced diarrhea in a piglet model involving enteric glia modulation and immune cells infiltration. Nutrients, 2022, 14, 5120.

(5) Cui Z, Wang X, Liao S, Qi M, Zha A, Zuo G, Liao P, Chen Y, Guo C, Tan B^*. Effects of medium-chain fatty acid glycerides on nutrient metabolism and energy utilization in weaned piglets. Frontiers In Veterinary Science, 2022, 9:938888.

(6) Hussain T, Murtaza G, Kalhoro DH, Kalhoro MS, Yulong Yin YL, Chughtai MI, Tan B^*, Yaseen A, Rehman ZU. Understanding the immune system in fetal protection and maternal infections during pregnancy. Journal Of Immunology Research, 2022, 2022:Article ID 7567708

(7) Qi M, Liao S, Wang J, Deng Y, Zha A, Shao Y, Cui Z, Song T, Tang Y^*, Tan B^*, Yin Y. MyD88 deficiency ameliorates weight loss caused by intestinal oxidative injury in an autophagy-dependent mechanism. Journal of Cachexia, Sarcopenia and Muscle, 2022, 13(1):677-695

(8) Tang Y, Liao S, Liu G, Xiong X, Liu H, Li F, Tan Z, Kong X, Yin Y, Tan B^*. Advanced single-cell pooled CRISPR screening identifies C19orf53 required for cell proliferation based on mTORC1 regulators. Cell Biology and Toxicology, 2022, 38:43–68

(9) Qi M, Tan B^*, Wang J, Liao S, Deng Y, Ji P, Song T, Zha A, Yin Y. The microbiota–gut–brain axis: A novel nutritional therapeutic target for growth retardation. Critical Reviews in Food Science and Nutrition, 2022, 62(18): 4867-4892.

(10) Duanmu Q, Tan B^*, Wang J, Huang B, Li J, Kang M, Huang K, Deng Q, Yin Y. The amino acids sensing and utilization in response to dietary aromatic amino acid supplementation in LPS-induced inflammation piglet model. Frontiers in Nutrition.2022, 8:819835.

(11) Wang J, Wang N, Qi M, Li J, Tan B^*. Glutamine, glutamate, and aspartate differently modulate energy homeostasis of small intestine under normal or low energy status in piglets . Animal Nutrition, 2022, 8 :216-226

(12) Hussain T, Murtaza G, Metwally E, Kalhoro DH, Kalhoro MS, Rahu BA, Sahito RGA, Yin Y, Yang H, Chughtai MI, Tan B^*. The role of oxidative stress and antioxidant balance in pregnancy. Mediators of Inflammation, 2021,2021:Article ID 9962860.

(13) Luo Z, Zhao Y, Zeng L, Yin J, Zeng Q, Li X, He J, Wang J, Tan B^*.  Effects of Fermented Radix puerariae Residue on Nutrient Digestibility and Reproductive Performance of Sows. Frontiers in Nutrition, 2021, 8:715713.

(14) Wang J, Xiao YX, Li JJ, Qi M, Tan B^*. Serum biochemical parameters and amino acids metabolism are altered in piglets by early-weaning and proline and putrescine supplementations. Animal Nutrition, 2021, 7(2):334-345.

(15) Hussain T*, Tan B^*, Murtaza G, Metwally E, Yang H, Kalhoro MS, Kalhoro DH, Chughtai MI and Yin Y. Role of dietary amino acids and nutrient sensing system in pregnancy associated disorders. Frontiers in Pharmacology,2020, 11:586979.

(16) Jiang Q, Yin J*, Chen J, Ma X, Wu M, Liu G, Yao K, Tan B*, Yin Y. Mitochondria-Targeted Antioxidants: A Step towards Disease Treatment. Oxidative Medicine and Cellular Longevity, 2020, Article ID 8837893.

(17) Wang J, Tan B*, Li J, Kong X, Tan M, Wu G, Regulatory role of L-proline in fetal pig growth and intestinal epithelial cell proliferation, Animal Nutrition, 2020,6:438-446..

(18) Chen S, Wu X, Xiao Y, Wang W, Liao S, Li F, Yin J, Ren W, Tan B*, Yin Y*. Effects of dietary gamma-aminobutyric acid supplementation on amino acid profile, intestinal immunity, and microbiota in ETEC-challenged piglets. Food Funct. 2020, 11(10):9067-9074

(19) Cui Z, Wang X, Hou Z, Liao S, Qi M, Zha A, Yang Z, Zuo G, Liao P, Chen Y*, Tan B*. Low-protein diet supplemented with medium-chain fatty acid glycerides improves the growth performance and intestinal function in post-weaning piglets. Animals, 2020, 10, 1852

(20) Liu H, Tan B*, Kong X*, Li J, Li G, He L, Bai M, Yin Y. Dietary insect powder protein sources improve protein utilization by regulation on intestinal amino acid-chemosensing system. Animals, 2020, 10, 1590

(21) Qi M, Tan B*, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y. Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model. Journal of Cellular Physiology.2021, 236(4):2631-2648.

(22) Zha A, Cui Z, Qi M, Liao S, Chen L, Liao P*, Tan B*. Dietary baicalin zinc supplementation alleviates oxidative stress and enhances nutrition absorption in deoxynivalenol challenged pigs. Current Drug Metabolism, 2020, 21(8):614-625.

(23) Li M^#, Yuan D^#, Liu Y, Jin H, Tan B*. Dietary puerarin supplementation alleviates oxidative stress in the small intestines of diquat-challenged piglets. Animals, 2020, 10, 631.

(24) Qi M, Wang J, Tan B*, Li J, Liao S, Liu Y, Yin Y, Dietary glutamine,glutamate, and aspartate supplementation improves hepatic lipid metabolism in post-weaning piglets, Animal Nutrition, 2020, 6(2):124-129.

(25) Xiao H, Zha C, Shao F, Wang L, Tan B*. Amino acids regulate energy utilization through mammalian target of rapamycin complex 1 and adenosine monophosphate activated protein kinase pathway in porcine enterocytes, Animal Nutrition, 2020, 6(1):98-106.

(26) Wang X, Tan B*, Liao P, Cui Z, Zhang S, Li X, Yin Y, Xiao D*. Functional bioactive substance improves the growth performance, antioxidant capacity and immune function of growth retardation pigs. Food and Agricultural Immunology, 2020, 31(1):329-340.

(27) Hussain T, Yuan D^*, Tan B^*, Murtaza G, Rahu N, Kalhoro MS, Kalhoro D, Yin Y. Eucommia ulmoides flavones (EUF) abrogated enterocyte damage induced by LPS involved in NF-κB signaling pathway. Toxicology In-vitro, 2020, 62:104674

(28) Hussain T, Tan B*, Murtaza G, Liu G, Rahu N, Kalhoro MS, Kalhoro DH, Adebowale TO, Mazhar MU, Rehman Z, Martínez Y, Khan SA, Yin Y. Flavonoids and Type 2 Diabetes: Evidence of efficacy in clinical and animal studies and delivery strategies to enhance their therapeutic efficacy. Pharmacological Research, 2020,152: 104629

(29) 李万全,查安东,谭碧娥*. 菌群代谢物氧化三甲胺调控畜禽脂肪沉积的研究进展. 中国畜牧杂志,2023,59(5):40-47.

(30) 崔志娟，齐鸣，谭碧娥*.中链脂肪酸甘油三酯在仔猪中的消化吸收及生理功能. 动物营养学报，2021，33(10):5441-5448.

(31) 齐鸣，谭碧娥*.自噬调节动物氧化应激反应的分子机制. 动物营养学报，2020, 32(9):3993-4002.

(32) 谭碧娥，伍树松，贺建华，印遇龙. 地方猪耐粗饲料和肉质性状形成的微生物代谢机制. 动物营养学报，2020，32(7):2941-2946.

(33) 罗振福, 贺建华, 谭碧娥*. 甜菜粕的资源化利用及其在猪营养中的应用. 家畜生态学报, 2020, 41(1):81-85.